Musashi-1 Rat, Clone: 14H1, eBioscience™

Rat Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9896-82


UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 15258217

Quantity Price
1 £176.00 / 100µg
Estimated Shipment date
from Supplier 27-10-2016
Add to basket

Description and Specification


Antigen Musashi-1
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Clone 14H1
Concentration 0.5mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Rat
Isotype IgG2a
Quantity 100μg
Regulatory Status RUO
Species Reactivity Human, Mouse, Rat
Storage Requirements Store at 2-8°C. Avoid repeated freeze/thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

This 14H1 monoclonal antibody recognizes human Musashi-1 (MSI-1), a 39kDa RNA binding protein. Musashi-1 is expressed in CNS stem and progenitor cells with decreased expression in differentiating cells. Musashi-1 functions as a translational repressor, directly regulating its target proteins, Numb and p21 (CIP1). Musashi-1 has been shown to be expressed in stem cells in a variety of other tissues such as the gut, stomach, mammary gland, and hair follicles. In addition to normal tissue expression, Musashi-1 expression has been identified in cells from several tumor types, mainly pulmonary and adenocarcinoma, as well as large and small cell carcinomas. Recently, expression of Musashi-1 in ischemic lesions following stroke provides evidence for neurogenesis as well as the role of Musashi-1 in regulating apoptosis.

Musashi-1 is highly conserved and the 14H1 antibody also recognizes mouse and rat Musashi-1.