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Invitrogen™ Munc13-4 Recombinant Rabbit Monoclonal Antibody (K01_3K44)
Description
Munc13-4 Recombinant Monoclonal Antibody for Western Blot
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Specifications
Specifications
| Antigen | Munc13-4 |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_3K44 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 0.05% BSA, 40% glycerol, 150mM NaCl and 0.01% sodium azide; pH 7.4 |
| Gene | Unc13d |
| Gene Accession No. | B2RUP2, Q70J99 |
| Gene Alias | 2610108D09Rik; FHL3; HLH3; HPLH3; Jinx; likely ortholog of H. sapiens unc-13 homolog D (UNC13D); mFLJ00067; munc 13-4; Munc13-4; Protein unc-13 homolog D; unc-13 homolog D; unc-13 homolog D (C. elegans); Unc13d |
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