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Invitrogen™ Munc13-4 Polyclonal Antibody
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Product Code. 13230149
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Quantity:
100 μL
Unit Size:
100µg
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13230149 100 μL 100µg
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Product Code. 13230149 Supplier Invitrogen™ Supplier No. PA521905

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Jurkat, K562. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Munc13-4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Unc13d
Gene Accession No. Q70J99
Gene Alias 2610108D09Rik; FHL3; HLH3; HPLH3; Jinx; likely ortholog of H. sapiens unc-13 homolog D (UNC13D); mFLJ00067; munc 13-4; Munc13-4; Protein unc-13 homolog D; unc-13 homolog D; unc-13 homolog D (C. elegans); Unc13d
Gene Symbols Unc13d
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Munc 13-4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 201294
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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