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MUC5AC Antibody (45M1), Novus Biologicals™

Product Code. 18429681 Shop All Bio Techne Products
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20 ug
Unit Size:
20µg
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18429681 20 ug 20µg
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Product Code. 18429681 Supplier Novus Biologicals Supplier No. NBP21519620ug

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Description

Mouse Monoclonal Antibody has been used in 12 publications

MUC5AC Monoclonal specifically detects MUC5AC in Human, Mouse, Rat, Porcine, Chicken, Feline, Mammal, Monkey, Rabbit, Bovine (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Dot Blot, Flow (Intracellular).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Mucin 5AC
Classification Monoclonal
Clone 45M1
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5ug/ml, Flow (Intracellular)
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P98088
Gene Alias gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin
Gene Symbols MUC5AC
Host Species Mouse
Immunogen M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
Purification Method Protein G purified
Quantity 20 ug
Regulatory Status RUO
Research Discipline Extracellular Matrix
Primary or Secondary Primary
Gene ID (Entrez) 4586
Test Specificity This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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