Invitrogen™ MUC20 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA550238

Product Code. 15694165

Description

The antibody detects endogenous levels of total MUC20 protein.

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: MUC20
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Muc20
• Gene Alias: BC026367; KIAA1359; Muc20; MUC-20; mucin 20; mucin 20, cell surface associated; mucin-20; transmembrane mucin MUC20S; UNQ2782/PRO7170
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 200958, 224116
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q8BUE7, Q8N307
• Gene Symbols: Muc20
• Immunogen: Fusion protein corresponding to residues near the C terminal of human mucin 20, cell surface associated.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG