MUC2 Antibody (CCP58), Biotin, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-33157B

Product Code. 18163042

Description

MUC2 Monoclonal specifically detects MUC2 in Human samples. It is validated for Western Blot, Immunohistochemistry-Paraffin.

Specifications

• Antigen: MUC2
• Classification: Monoclonal
• Conjugate: Biotin
• Gene Alias: Intestinal mucin-2, MLP, MUC-2, mucin 2, intestinal/tracheal, mucin 2, oligomeric mucus/gel-forming, mucin-2, mucin-like protein, SMUC
• Host Species: Mouse
• Molecular Weight of Antigen: 520 kDa
• Quantity: 0.1 mL
• Research Discipline: Cancer, Cellular Markers, Inflammation, Signal Transduction
• Gene ID (Entrez): 4583
• Target Species: Human
• Form: Purified

• Applications: ELISA
• Clone: CCP58
• Dilution: ELISA
• Gene Symbols: MUC2
• Immunogen: A synthetic peptide of 29 amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT from MUC2 protein, coupled to KLH. (Uniprot: Q02817)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This monoclonal antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP(GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

For Research Use Only