Invitrogen™ MTRR Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5113498

Product Code. 17181354

Description

MTRR Polyclonal Antibody for Western Blot, IHC (P), ELISA

Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: MTRR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MTRR
• Gene Alias: [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing); 4732420G08; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase; aqCbl reductase; aquacobalamin reductase; cblE; Methionine synthase reductase; methionine synthase reductase, mitochondrial; MGC129643; MSR; Mtrr
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 4552
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 4 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q9UBK8
• Gene Symbols: MTRR
• Immunogen: Recombinant Human Methionine synthase reductase protein (1-725AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG