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Invitrogen™ MTCH2 Polyclonal Antibody
Description
A suggested positive control is 293 cell lysate. PA5-20696 can be used with blocking peptide PEP-0811.
MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.
Specifications
Specifications
| Antigen | MTCH2 |
| Applications | Immunohistochemistry, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | Mtch2 |
| Gene Accession No. | Q791V5, Q9Y6C9 |
| Gene Alias | 2310034D24Rik; 4930539J07Rik; HSPC032; Met-induced mitochondrial protein; MIMP; mitochondrial carrier 2; mitochondrial carrier homolog 2; mitochondrial carrier homolog 2 (C. elegans); Mtch2; SLC25A50; solute carrier family 25, member 50 |
| Gene Symbols | Mtch2 |
| Show More |
Product Title
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