MT-ATP6 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA5116789

Product Code. 17209293

Description

Positive Samples: HeLa, U-251MG, mouse brain, mouse heart, mouse kidney, rat kidney Immunogen sequence: PPLLIPTSKY LINNR

The MT-ATP6 gene provides information for making a protein that is essential for normal mitochondrial function. Mitochondria are structures within cells that convert the energy from food into a form that cells can use. These cellular structures produce energy through a process called oxidative phosphorylation, which uses oxygen and simple sugars to create adenosine triphosphate (ATP), the cell's main energy source. The MT-ATP6 protein forms one part (subunit) of a large enzyme called ATP synthase. This enzyme, which is also known as complex V, is responsible for the final step of oxidative phosphorylation. Specifically, one segment of ATP synthase allows positively charged particles, called protons, to flow across a specialized membrane inside mitochondria. Another segment of the enzyme uses the energy created by this proton flow to convert a molecule called adenosine diphosphate (ADP) to ATP.

Specifications

• Antigen: MT-ATP6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MT-ATP6
• Gene Alias: ATP synthase F0 subunit 6; ATP synthase subunit a; Atp6; ATPase6; F-ATPase protein 6; mitochondrially encoded ATP synthase 6; Mtatp6; MT-ATP6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17705, 26197, 4508
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2.14 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P00846, P00848, P05504
• Gene Symbols: MT-ATP6
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MT-ATP6 (YP_0030240311)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG