Invitrogen™ Human MST4, GST Tag Recombinant Protein

Product Code. 11523517

Brand: Invitrogen™ PV3690

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

MST4 is member of the Ste20-like kinase family of serine/threonine kinases and is overexpressed during prostate cancer development. The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Specifications

• Accession Number: Q9P289
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris with 50% glycerol, 0.02% Triton X-100, 150mM NaCl, 2mM DTT, 0.5mM EDTA and no preservative; pH 7.5
• Gene ID (Entrez): 51765
• Molecular Weight (g/mol): 75.7 kDa
• Name: Human MST4, GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: 2610018G03Rik; Mammalian STE20-like protein kinase 4; mammalian sterile 20-like 4; Mask; Mst3 and SOK1-related kinase; Mst4; MST-4; OTTHUMP00000215132; OTTHUMP00000215134; RGD1563568; RP6-213H19.1; serine/threonine kinase 26; serine/threonine protein kinase 26; serine/threonine protein kinase MST4; serine/threonine-protein kinase 26; Serine/threonine-protein kinase MASK; serine/threonine-protein kinase MST4; STE20-like kinase 4; STE20-like kinase MST4; STK26
• Common Name: MST4
• Gene Symbol: Stk26
• KinaseFamily: STE20 Kinase Family
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Assay Entry: Biochemical terbium phospho-specific activity, Biochemical phospho-specific activity (no antibody)
• Kinase Group: Ser/Thr Kinases: STE Group
• Shipping Condition: Dry Ice
• System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate, Zin-LYTE™
• Target Entry: MST4
• Target Gene: serine/threonine protein kinase MST4
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Full Length
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Drug Discovery: Oncology, Signal Transduction