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Invitrogen™ MSRA Polyclonal Antibody
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Product Code. 16506771
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100 μL
Unit Size:
100µL
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16506771 100 μL 100µL
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Product Code. 16506771 Supplier Invitrogen™ Supplier No. PA588562

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GNSASNIVSP QEALPGRKEQ TPVAAKHHVN GNRTVEPFPE GTQMAVFGMG CFWGAERKFW VLKGVYSTQV GFAGGYTSNP TYKEVCSEKT GHAEVVRVVY QPEHMSFEEL LKVFWENHDP TQGMRQGNDH GTQYRSAIYP TSAKQMEAAL SSKENYQKVL SEHGFGPITT DIREGQTFYY AEDYHQQYLS KNPNGYCGLG GTGVSCPVGI KK; Positive Samples: Mouse kidney, Rat kidney; Cellular Location: Cytoplasm, Lipid-anchor, Membrane, Mitochondrion, Nucleus.

Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MSRA
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.21 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Msra
Gene Accession No. Q923M1, Q9D6Y7, Q9UJ68
Gene Alias 2310045J23Rik; 6530413P12Rik; cytosolic methionine-S-sulfoxide reductase; methionine sulfoxide reductase A; mitochondrial peptide methionine sulfoxide reductase; Msra; MSR-A; peptide met (O) reductase; peptide Met(O) reductase; peptide methionine sulfoxide reductase; peptide-methionine (S)-S-oxide reductase; PMSR; protein-methionine-S-oxide reductase
Gene Symbols Msra
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 24-235 of human MSRA (NP_0364631).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110265, 29447, 4482
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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