Invitrogen™ MSC Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA131456

Product Code. 11546103

Description

Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX21330-PEP).. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many musclespecific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to represses MyoD activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation.

Specifications

• Antigen: MSC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MSC
• Gene Alias: ABF1; ABF-1; Activated B-cell factor 1; activated B-cell factor 1, homolog of mouse musculin; activated B-cell factor-1; bHLHa22; Class A basic helix-loop-helix protein 22; Msc; Musculin; myogenic repressor; Myor
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9242
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O60682
• Gene Symbols: MSC
• Immunogen: Peptide with sequence C-PLKSDWNSLDGIIR, from the C Terminus.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG