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MRTX-1257, MedChemExpress

Product Code. 16434838
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Quantity:
5 mg
10 mg
Unit Size:
10mg
5mg
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Product Code. 16434838

Brand: Medchem Express HY114436

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This item is not returnable. View return policy

Description

MedChemExpress MRTX-1257 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells.

MRTX-1257 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells.

Specifications

Chemical Name or Material MRTX-1257
Physical Form Solid
CAS 2206736-04-9
Color Light Yellow
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C33H39N7O2
For Use With (Application) Cancer-Kinase/protease
Solubility Information DMSO : 55 mg/mL (97.22 mM; Need ultrasonic)
SMILES N#CC[C@@H]1N(C(C=C)=O)CCN(C2=C3C(CN(C4=C5C(C)=CC=CC5=CC=C4)CC3)=NC(OC[C@H]6N(C)CCC6)=N2)C1
Molecular Weight (g/mol) 565.71
Formula Weight 565.71
Percent Purity 98.03%
Grade Research
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Research purposes only

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