Invitrogen™ MRPS18B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA588338

Product Code. 16556611

Description

Immunogen sequence: MAASVLNTVL RRLPMLSLFR GSHRVQVPLQ TLCTKAPSEE DSLSSVPISP YKDEPWKYLE SEEYQERYGS RPVWADYRRN HKGGVPPQRT RKTCIRRNKV VGNPCPICRD HKLHVDFRNV KLLEQFVCAH TGIIFYAPYT GVCVKQHKRL TQAIQKARDH GLLIYHIPQV EPRDLDFSTS HGAVSATPPA PTLVSGDPWY PWYNWKQPPE RELSRLRRLY QGHLQEESGP PPESMPKMPP RTPAEASSTG QTGPQSAL; Positive Samples: U-87MG, A-431, Mouse kidney, Mouse brain, Rat heart, Rat kidney; Cellular Location: Mitochondrion.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.

Specifications

• Antigen: MRPS18B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPS18B
• Gene Alias: 2400002C15Rik; 28S ribosomal protein S18-2, mitochondrial; 28S ribosomal protein S18b, mitochondrial; C6orf14; HSPC183; HumanS18a; mitochondrial ribosomal protein S18-2; mitochondrial ribosomal protein S18B; Mitochondrial small ribosomal subunit protein bS18b; Mitochondrial small ribosomal subunit protein mS40; MRP-S18-2; MRPS18-2; MRPS18B; MRP-S18-b; mrps18-b; PTD017; S18amt; S18mt-b
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28973, 294230, 66973
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 4.53 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q99N84, Q9Y676
• Gene Symbols: MRPS18B
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-258 of human MRPS18B (NP_0547651).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG