Invitrogen™ MRPS11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA560497

Product Code. 15738331

Description

Immunogen sequence: GFRNAKKGTG IAAQTAGIAA AARAKQKGVI HIRVVVKGLG PGRLSAMHGL IMGGLEVISI TDNTPIPHNG Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: MRPS11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPS11
• Gene Alias: 0710005I03Rik; 28S ribosomal protein S11, mitochondrial; C79873; Cervical cancer proto-oncogene 2 protein; HCC2; HCC-2; mitochondrial ribosomal protein S11; Mitochondrial small ribosomal subunit protein uS11m; MRPS11; MRP-S11; RGD1559901; RPMS11; S11mt
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64963
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P82912
• Gene Symbols: MRPS11
• Immunogen: Recombinant protein corresponding to Human MRPS11. Recombinant protein control fragment (Product #RP-100639).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG