Invitrogen™ MRPL46 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA590459

Product Code. 16517851

Description

Immunogen sequence: MAAPVRRTLL GVAGGWRRFE RLWAGSLSSR SLALAAAPSS NGSPWRLLGA LCLQRPPVVS KPLTPLQEEM ASLLQQIEIE RSLYSDHELR ALDENQRLAK KKADLHDEED EQDILLAQDL EDMWEQKFLQ FKLGARITEA DEKNDRTSLN RKLDRNLVLL VREKFGDQDV WILPQAEWQP GETLRGTAER TLATLSENNM EAKFLGNAPC GHYTFKFPQA MRTESNLGAK VFFFKALLLT GDFSQAGNKG HHVWVTKDEL GDYLKPKYLA QVRRFVSDL; Positive Samples: Mouse brain; Cellular Location: Mitochondrion.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.

Specifications

• Antigen: MRPL46
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL46
• Gene Alias: 3110052F15Rik; 39S ribosomal protein L46, mitochondrial; C15orf4; C80107; L46mt; LIECG2; Mitochondrial large ribosomal subunit protein mL46; mitochondrial ribosomal protein L46; Mrpl46; MRP-L46; P2ECSL
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26589, 67308
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.57 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9EQI8, Q9H2W6
• Gene Symbols: MRPL46
• Immunogen: Recombinant protein (or fragment).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG