Invitrogen™ MRPL4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5101674

Product Code. 16608154

Description

Antibody detects endogenous levels of total MRPL4.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified alternatively spliced variants that encode different protein isoforms.

Specifications

• Antigen: MRPL4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL4
• Gene Alias: 1110017G11Rik; 39S ribosomal protein L4, mitochondrial; CDABP0091; CGI-28; L4mt; Mitochondrial large ribosomal subunit protein uL4m; mitochondrial ribosomal protein L4; MNCb-3848; MRPL4; MRP-L4; rm04
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51073, 66163
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9BYD3, Q9DCU6
• Gene Symbols: MRPL4
• Immunogen: A synthesized peptide derived from human MRPL4(Accession Q9BYD3), corresponding to amino acid residues T89-G139.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG