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Invitrogen™ MRP7 Polyclonal Antibody
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Product Code. 15654465
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Quantity:
100 μL
Unit Size:
100µL
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15654465 100 μL 100µL
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Product Code. 15654465 Supplier Invitrogen™ Supplier No. PA550536

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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total ABCC10 protein.

The MRP family is represented by nine similar ABC transporters that have the ability to transport structurally diverse lipophilic anions and operate as chemical efflux pumps. MRP7 (multidrug resistance-associated protein 7, ATPbinding cassette sub-family C member 10) is a multi-pass membrane protein that belongs to the ABC transporter family (conjugate transporter subfamily). MRP7 is involved with the ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG). MRP7 is also probably involved in cellular detoxification through its lipophilic anion extrusion capabilities. MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains. MRP7 likely has three isoforms. Isoform 2 is the most widely expressed, while isoform 1 is predominately expressed in the spleen.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRP7
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene ABCC10
Gene Accession No. Q5T3U5
Gene Alias ABCC10; ATP binding cassette subfamily C member 10; ATP-binding cassette sub-family C member 10; ATP-binding cassette, subfamily C (CFTR/MRP), member 10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; EST182763; mFLJ00002; Mrp7; Multidrug resistance-associated protein 7; SIMRP7
Gene Symbols ABCC10
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family C (CFTR/MRP), member 10.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 89845
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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