Invitrogen™ MRP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA585631

Product Code. 16352565

Description

Keep as concentrated solution. Predicted reactivity: Rhesus Monkey (100%). Positive Control: A549, A549 membrane extract. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: MRP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABCC2
• Gene Alias: ABC30; Abcc2; AI173996; ATP binding cassette subfamily C member 2; ATP-binding cassette sub-family C member 2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; calicular multispecific organic anion transporter; canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter 1; Cmoat; CMOAT1; Cmrp; DJS; Human MRP2; KIAA1010; MRP2; multidrug resistance associated protein 2; multidrug resistance protein 2; multidrug resistance-associated protein 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1244
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.76 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q92887
• Gene Symbols: ABCC2
• Immunogen: Synthetic peptide encompassing a sequence within the Intracellular domain of human MRP2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG