Invitrogen™ MRCK alpha Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA568391

Product Code. 15853224

Description

Predicted to react with Mouse and Rat samples.

CDC42BPA (MRCKA) is a serine/threonine kinase which functions in actin cytoskeleton assembly and organization. Three independent coiled-coil domains and the N-terminal region preceding the kinase domain are responsible for intermolecular interactions leading to MRCK alpha multimerization. The transautophosphorylation process is critical for regulation of MRCK alpha catalytic activities. Binding of phorbol esters to MRCK releases its autoinhibition, allowing N-terminal dimerization and subsequent kinase activation.

Specifications

• Antigen: MRCK alpha
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDC42BPA
• Gene Alias: A930014J19Rik; CDC42 binding protein kinase alpha; CDC42 binding protein kinase alpha (DMPK-like); CDC42 binidng protein kinase beta; CDC42-binding protein kinase alpha; CDC42-binding protein kinase alpha (DMPK-like); CDC42BPA; cdc42bpa {ECO:0000250; DKFZp686L1738; DKFZp686P1738; DMPK-like; DMPK-like alpha; FLJ23347; Kiaa0451; MRCK; MRCK alpha; MRCKA; myotonic dystrophy kinase-related CDC42-binding kinase alpha; myotonic dystrophy kinase-related CDC-42-binding kinase-alpha; myotonic dystrophy kinase-related CDC42-binding protein kinase alpha; myotonic dystrophy protein kinase-like alpha; mytonic dystrophy kinase-related Cdc42-binding kinase; PK428; RP5-1087E8.4; serine/threonine-protein kinase MRCK alpha; ser-thr protein kinase PK428; ser-thr protein kinase related to the myotonic dystrophy protein kinase; UniProtKB:Q5VT25}
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114116, 226751, 8476
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.6 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O54874, Q3UU96, Q5VT25
• Gene Symbols: CDC42BPA
• Immunogen: Synthetic peptide corresponding to residues near the C terminal of human MRCK alpha.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG