Invitrogen™ MPP5 Polyclonal Antibody

Sheep Polyclonal Antibody

Brand:  Invitrogen™ PA5149435

Product Code. 30534865

Description

Reconstitute at 0.2 mg/mL in sterile PBS.

MPP5 (Membrane Protein, Palmitoylated 5) plays a critical role in neurogenesis and hematopoiesis. This protein is crucial for establishing and maintaining cell polarity in epithelial cells and neurons. It is involved in the Par-3 complex, which contributes to maintaining tight junctions in epithelial cells. Mutations in MPP5 have been associated with severe neurologic impairments, including global developmental delay (GDD) and behavioral changes. In animal models, MPP5 is highly involved in the early differentiation of multipotent progenitors and supports long-term lineage-specific contributions, primarily in myeloid and lymphoid cells. MPP5 variants disrupt normal cellular function, leading to profound developmental and functional abnormalities.

Specifications

• Antigen: MPP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MPP5
• Gene Alias: 3830420B02Rik; AI255216; AI644496; FLJ12615; MAGUK p55 subfamily member 5; membrane palmitoylated protein 5; membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 5); membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); MPP5; palmitoylated 5; PALS1; protein associated with Lin Seven 1; protein associated with Lin-7 1; stardust
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 314259, 56217, 64398
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: Q8N3R9, Q9JLB2
• Gene Symbols: MPP5
• Immunogen: E. coli-derived recombinant human PALS1/MPP5, Ala392-Ser509.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG