Invitrogen™ MPP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA521526

Product Code. 13209098

Description

Recommended positive controls: A549, HeLa, HCT116, mouse brain. Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (82%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression and signaling. The MAGUK family is divided into four subfamilies: DLG-like, ZO1-like, p55-like and LIN2-like. MPP2 (membrane protein, palmitoylated 2), also known as MAGUK p55 subfamily member 2, discs large homolog 2 or DLG2, is a 576 amino acid protein belonging to the MAGUK family that exists as three alternatively spliced isoforms. MPP2 contains one guanylate kinase-like domain, a PDZ (DHR) domain, two L27 domains and a single SH3 domain. The gene encoding MPP2 maps to the same segment of human chromosome 17 as MPP3, with whom MMP2 likely shares similar function and common structural organization.

Specifications

• Antigen: MPP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mpp2
• Gene Alias: D11Bwg0652e; discs large homolog 2; discs large, homolog 2; Dlg2; Dlgh2; MAGUK p55 subfamily member 2; membrane palmitoylated protein 2; membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2); Mpp2; p55 subfamily member of MAGUK family; palmitoylated membrane protein 2; Pals4; Protein MPP2; rCG_34691
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4355, 50997
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.61 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q14168, Q9WV34
• Gene Symbols: Mpp2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human MPP2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG