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Invitrogen™ VCAM-1 Mouse ELISA Kit

Sandwich ELISA Kit

Brand:  Invitrogen™ EMVCAM1

Code : NEW

Additional Details : Weight : 0.33000kg

Product Code. 15445353

  • £398.00 / 1 set


Estimated Shipment date
from Supplier 22-06-2020
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Includes: Pre-coated plate(s), standard, detector antibody, HRP conjugate, diluents, wash buffer, chromogen, stop solution, and plate covers.

Description

Description

VCAM-1 (vascular cell adhesion protein 1, CD106, INCAM-110) is a cell surface sialoglycoprotein expressed by cytokine activated endothelium. VCAM-1 has a number of functions including the regulation of leukocyte migration, leukocyte-endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases. VCAM-1 is distributed across non-leukocyte and leukocyte cells. VCAM-1 expression is reportedly correlated with adhesion of melanoma, Burkitt lymphoma, osteosarcoma, and kidney carcinoma but not colon carcinoma cells to endothelial cells which may determine the site of tumor metastasis. VCAM-1 is a member of the Ig superfamily of adhesion molecules, is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on unstimulated endothelial cells. VCAM-1 is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. VCAM-1 serves as a ligand for leukocyte integrin alpha-beta (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. VCAM-1 plays a role in tumor metastasis, and may also be involved in the development of atherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms of VCAM-1 have been described.
Specifications

Specifications

P29533
Colorimetric Microplate Reader
2.05-500 pg/mL
Biotin
ELISA, Protein Assays, Protein Biology, Cancer Biology, Immunology, Neuroscience, Neurobiology, Protein Detection, Protein Analysis
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Anti-mouse VCAM-1 precoated 96-well strip plate, lyophilized recombinant mouse VCAM-1 standard, 20X wash buffer, biotinylated antibody reagent, streptavidin-HRP reagent, TMB substrate, stop solution, contains 0.2M sulfuric acid, assay diluent (5X concentr
1 Kit
1.5 pg/mL
Plasma, 1 μL|Serum, 1 μL|Supernatant, 100 μL
2°C to 8°C
1 hr. 20 min.
Mouse
VCAM-1
Other Proteins
CD106,Vcam-1
<12%
96 Tests
Supernatant
Colorimetric
HRP
1.5pg/mL to 500pg/mL
VCAM-1 ELISA Kit, 96 Assays, 1 Kit, Mouse Species, Streptavidin-HRP Conjugate, Colorimetric Detection Method, Enzyme-Linked Immunosorbent Assay Designed for the Quantitation and Detection of VCAM-1 in Samples Using a Microplate Reader
22329
ELISA Kit
RUO
100 μL per sample after dilution
This ELISA kit shows no cross-reactivity with any of the cytokines tested: Mouse 6Ckine, CTACK, Eotaxin, GCSF, GM-CSF, IL-2, IL-3, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p40, IL-12p70, IL-13, IL-17, IFN-gamma, KC, Leptin, MCP-5, MIP-1 alpha, MIP-2, MIP-3 bet
96 Assays
4 hr. 45 min.
Solid-phase sandwich ELISA
Mouse
Development
CD106, Vcam-1
<10%
Mouse
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