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STEMCELL Technologies Mouse Recombinant SDF-1 alpha (CXCL12)

Product Code. 17179611
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Quantity:
25 μg
5 μg
Unit Size:
25µg
5µg
This item is not returnable. View return policy

Product Code. 17179611

Brand: STEMCELL Technologies 78121.1

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This item is not returnable. View return policy

Description

Stromal cell-derived factor 1 alpha

  • Stromal cell-derived factor 1 alpha (SDF-1α) is a member of the CXC group of chemokines that binds to the G-protein coupled receptor, CXCR4, to regulate migration, proliferation, differentiation, and survival of many cell types including hematopoietic stem cells, B cells, and T cells
  • It is produced by bone marrow stromal cells, osteoblasts, endothelial cells, and neuronal cells
  • SDF-1α was first identified as the pre-B-cell growth-stimulating factor (PBSF) in the mouse bone marrow-derived stromal cell line, PA6, in the growth of B cell precursors
  • SDF-1α primarily regulates cell motility during development and adulthood, including the homing of hematopoietic stem cells and neutrophils to fetal bone marrow during ontogeny) and the recruitment of endothelial progenitor cells from bone marrow during angiogenesis in adulthood

Specifications

Name CXCL12, PBSF, SDF-1 α, Stromal cell-derived factor-1
Quantity 25 μg
Cell Type B Cells; Endothelial Cells; Epithelial Cells; Monocytes; T Cells
Purity or Quality Grade ≥95%
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