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STEMCELL Technologies Mouse Recombinant IL-33
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Quantity:
10 μg
1000 μg
Unit Size:
1000µg
10µg
Description
- Interleukin 33 (IL-33) is a pro-inflammatory cytokine from the IL-1 family
- It binds to the ST2 receptor and activates NF-kB and MAPK pathways
- IL-33 is expressed by epithelial cells, smooth muscle cells, and fibroblasts in various tissues and organs, as well as resting basophils, mast cells, eosinophils, natural helper cells, group 2 innate lymphoid cells, dendritic cells, and activated macrophages (Schmitz et al.; Yasuda et al.) It contributes to allergic inflammation by stimulating production of the cytokines IL-4, IL-5, and IL-13 in Th2 cells, and stimulates host defense against microbial and viral infections (Liew; Yasuda et al.) In the central nervous system, IL-33 is produced by endothelial cells and astrocytes
- It induces proliferation of microglia and mediates production of pro-inflammatory cytokines (Yasuoka et al.)
Specifications
Specifications
| Name | IL-1F11, Interleukin-33 |
| Quantity | 1000 μg |
| Cell Type | Monocytes; T Cells, Other Subsets |
| Purity or Quality Grade | >95% |
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