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STEMCELL Technologies Mouse Recombinant IL-21

Product Code. 17169601
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Quantity:
1000 μg
50 μg
Unit Size:
1000µg
50µg
This item is not returnable. View return policy

Product Code. 17169601

Brand: STEMCELL Technologies 78116.1

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This item is not returnable. View return policy

Description

Interleukin 21

  • Interleukin 21 (IL-21) is a pleiotropic cytokine that is composed of four α-helical bundles and primarily produced by natural killer T (NKT) cells, T follicular helper (Tfh) cells, and Th17 cells
  • IL-21 signals via receptor heterodimerization of IL-21 receptor and IL-2 receptor subunit gamma (IL-2RG or CD132), both of which have a common gamma-chain subunit and activate the JAK/STAT, MAPK, and PI3K pathways
  • IL-21 has been shown to have a critical role in regulating immunoglobulin production and differentiation of the pro-inflammatory Th17 population of cells
  • Additionally, IL-21 specifically sustains CD8+ T cell effector activity and provides a mechanism of CD4+ T cell help during chronic viral infection

Specifications

Name Interleukin-21, Za11
Quantity 50 μg
Cell Type Mesenchymal Stem and Progenitor Cells; NK Cells; T Cells; T Cells, CD4+; T Cells, CD8+; T Cells, Other Subsets
Purity or Quality Grade ≥95%
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