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STEMCELL Technologies Mouse Recombinant IL-11

Product Code. p-7217574
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Product Code. 17149381

Brand: STEMCELL Technologies 78026

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Description

Interleukin 11

  • Interleukin 11 (IL-11) is a pleiotropic cytokine with effects on various tissues including the bone marrow, brain, and intestinal mucosa
  • It belongs to the IL-6 family of cytokines that share a common signal transducer, gp130
  • Culture of mouse bone marrow cells with IL-11 in combination with IL-3, IL-6, and stem cell factor induces significant expansion and proliferation of colony-forming cells in vitro
  • In addition, in combination with IL-3, IL-11 significantly enhances the growth of megakaryocytic colonies in vitro, suggesting its role in augmenting mouse megakaryopoiesis
  • IL-11 is expressed in a wide range of normal adult mouse tissues, including the central nervous system, thymus, lung, and bone
  • The mouse IL-11 cDNA was cloned using an expression library generated from the lipopolysaccharide-induced mouse fetal thymic cell line, T2

Specifications

Name Adipogenic inhibitory factor, AGIF, Interleukin-11, Oprelvekin
Quantity 100 μg
Cell Type B Cells; Hematopoietic Stem and Progenitor Cells; Other; Pluripotent Stem Cells; T Cells
Purity or Quality Grade ≥95%
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