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STEMCELL Technologies Mouse Recombinant IFN-gamma

Product Code. 15806044
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1000 μg
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100µg
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Product Code. 15806044

Brand: STEMCELL Technologies 78021

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This item is not returnable. View return policy

Description

Interferon-gamma

  • Interferon-gamma (IFN-γ), also known as type II interferon, is produced by T and NK cells, and in smaller amounts by dendritic cells and macrophages
  • IFN-γ is controlled by cytokines such as IL-12 and IL-18 secreted in response to infection
  • IFN-γ binds to a receptor complex and initiates signal transduction via the JAK/STAT pathway; this culminates in the transcription and activation of many genes that control a diverse array of immunological functions
  • IFN-γ stimulates the antimicrobial and anti-tumor activity of macrophages, NK cells, and neutrophils by promoting the activation of microbial effector functions such as production of reactive oxygen species, NO intermediates, complement, etc
  • IFN-γ enhances MHC class I and II expression in dendritic cells and mononuclear phagocytes, as well as the production of IL-12 by dendritic cells

Specifications

Name Interferon gamma, Type II interferon
Quantity 100 μg
Cell Type B Cells; Hematopoietic Stem and Progenitor Cells; Intestinal Cells; Mesenchymal Stem and Progenitor Cells; T Cells
Purity or Quality Grade ≥95%
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