eBioscience™ Mouse IL-7, Recombinant Protein

Mouse Recombinant Protein

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-8071-62

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15597486

Quantity Price
1 £ 127.8 / 5µg
Estimated Shipment date
from Supplier 05-06-2017
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Description and Specification

Specification

Purification Method SDS-PAGE
Validated Application FA
Conjugate Unlabeled
Structural Form E. coli expressed amino acids glu 26-ile 154 of mature mouse IL-7 accession # NM_008371
Accession Number NM_008371
Molecular Weight The methionylated polypeptide has a predicted molecular mass of 15,028. The DTT reduced protein migrates as a 15kDa polypeptide. The non-reduced protein has slightly higher mobility on non-reducing SDS-PAGE.
Purity >98%
Name IL-7
Biological Activity The ED50 of this protein, as measured by 2E8 cell proliferation assay, is less than or equal to 1.6ng/mL. This corresponds to a specific activity of greater than or equal to 6.3 x 105 Units/mg.
Regulatory Status RUO
Source E. coli
Cross Reactivity Mouse
Formulation Sterile liquid; 0.1M glycine, pH 3.0, 0.22μm filtered.
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
Recombinant Yes
Quantity 5μg
For Use With (Application) Cytokine Bioassays
Gene Symbol Interleukin-7, IL7

Mouse IL-7 (also called Lymphopoietin 1, LP-1), a pre-B cell growth factor, is an ∽25 kDa factor produced by bone marrow and thymic stromal cells, and spleen cells. IL-7 is a stromal cell-derived growth factor for progenitor B cells and T cells. The main population in the thymus responsive to IL-7 is CD4-CD8-. It also stimulates proliferation and differentiation of mature T cells and NK cells.