Gibco™ Mouse IL-17E (IL-25) Recombinant Protein, PeproTech®

Product Code. 17861693

Brand: Gibco™ 21017E500UG

Description

Recombinant Protein

Recombinant Murine IL-17E is a 35.0 kDa disulfide-linked homodimer of two 152-amino-acid polypeptide chains. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Interleukin 25 (IL-25) is a member of the IL-17 family and is identified as a proinflammatory cytokine which is produced by Th17 effector cells thus enabling the Th17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis. IL-25 also induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. IL-25 itself is activated through IL-23, IL-5, and TGF-beta.

Specifications

• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 140806
• Molecular Weight (g/mol): 35 kDa
• Name: Mouse IL-17 E (IL-25)
• Quantity: 500 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: D17Wsu104e; il 17 e; Il17e; IL-17 E; Il25; IL-25; ILN; Interleukin; interleukin 17 E; interleukin 25; interleukin-17 E; Interleukin-25; Ly6elg; Mydgf; myeloid derived growth factor; myeloid-derived growth factor; RGD1561632; UNQ3120/PRO10272; UPF0556 protein C19orf10 homolog
• Common Name: IL-25
• Gene Symbol: IL25
• Biological Activity: Measured by its ability to induce GROalpha (CXCL1) secretion in HT-29 human colon adenocarcinoma cells.
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: MLRIQEGCSH LPSCCPSKEQ EPPEEWLKWS SASVSPPEPL SHTHHAESCR ASKDGPLNSR AISPWSYELD RDLNRVPQDL YHARCLCPHC VSLQTGSHMD PLGNSVPLYH NQTVFYRRPC HGEEGTHRRY CLERRLYRVS LACVCVRPRV MA
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.