eBioscience™ Human M-CSF, Recombinant Protein

Human Recombinant Protein

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-8789-62

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Product Code. 15577546

Quantity Price
1 £ 36.08 / 5µg
EU Stock 1
Add to basket


Description and Specification

Specification

Product Type Recombinant Protein
Conjugate Unlabeled
Accession Number NM-172211
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
Regulatory Status RUO
Purity >98%
Quantity 5μg
Purification Method SDS-PAGE
Biological Activity The bioactivity of this protein, as determined in a cell proliferation assay on M-NFS-60 cells, is 3ng/mL. This corresponds to a specific activity of 3.3 X 105 Units/mg.
Source Insect Cells
Gene Symbol Macrophage colony stimulating factor, monocyte colony stimulating factor
Cross Reactivity Human
For Use With (Application) Cytokine Bioassays
Molecular Weight 36kDa
Storage Requirements Store at less than or equal to -70°C.
Recombinant Yes
Structural Form Human M-CSF Glu34-Ser190 accession # NM-172211 expressed in insect cells with a C-terminal 6X His tag.
Name M-CSF
Formulation Sterile liquid; phosphate-buffered saline 1% BSA, 0.22μm filtered.

Human Macrophage Colony Stimulating Factor (M-CSF, also called CSF-1) is a ∽36 kDa disulfide-linked homodimer produced by a variety of cells including fibroblasts, macrophages, bone marrow stromal cells and endothelial cells. M-CSF regulates macrophage survival, proliferation and differentiation. M-CSF also enhances macrophage killing of tumor cells and microorganisms and regulates cytokine production from macrophages.