Human IFN gamma, Recombinant Protein, Carrier-Free, Invitrogen™

Product Code. 15578776

Brand: eBioscience 34831982

Description

Human Recombinant Protein

Human IFN gamma is an ∽20 kDa factor produced by activated T, B and NK cells and is an anti-viral and anti-parasitic cytokine. IFN gamma in synergy with other cytokines, such as TNF alpha, inhibits proliferation of normal and transformed cells. Immunomodulatory effects of IFN gamma are exerted on a wide range of cell types expressing the high affinity receptors for IFN-γ. Glycosylation of IFN gamma does not affect its biological activity.

Specifications

• Accession Number: NM_000619
• Concentration: 0.5mg/mL
• For Use With (Application): Cytokine Bioassay
• Formulation: Sterile liquid: 20mM phosphate, 400mM NaCl, pH 7.2, 0.22μm filtered.
• Molecular Weight (g/mol): The methionylated N-terminal protein migrates as a 16kDa polypeptide on SDS-PAGE.
• Name: IFN gamma
• Purification Method: SDS-PAGE
• Quantity: 100 μg
• Source: E. coli
• Storage Requirements: Store at less than or equal to -70°C.
• Regulatory Status: RUO
• Structural Form: E. coli expressed amino acids Gln 24-Gln 166 of mature human IFN gamma accession # NM_000619
• Endotoxin Concentration: Less than 0.01ng/μg cytokine as determined by the LAL assay.
• Gene Symbol: Interferon-gamma
• Biological Activity: The ED50 of this protein, as measured by EMC virus protection assay using A549 cells, is less than or equal to 175pg/mL. This corresponds to a specific activity of greater than or equal to 5.7 x 10⁶ Units/mg.
• Product Type: Recombinant Protein, Carrier-Free
• Conjugate: Unconjugated
• Cross Reactivity: Human
• Recombinant: Recombinant
• Purity or Quality Grade: >98%