Gibco™ Mouse FGF-23 Recombinant Protein, PeproTech®

Product Code.	Quantity	unitSize
17813933	2 x 500 μg	1mg
17814363	100 μg	100µg
30088073	2 x 500 μg	Pack of 2
17844633	20 μg	20µg
17864273	250 μg	250µg
17804283	500 μg	500µg
17804123	5 μg	5µg

Product Code. 17813933

Brand: Gibco™ 450551MG

Description

Recombinant Protein

450-55-1MG will be provided as 2 x 500 μg (450-55-500UG). Recombinant Murine FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The protein encoded by this gene is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The product of this gene inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets, an inherited phosphate wasting disorder. Abnormally high level expression of this gene was found in oncogenic hypophosphatemic osteomalacia, a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations in this gene have also been shown to cause familial tumoral calcinosis with hyperphosphatemia.

Specifications

• Accession Number: Q9EPC2
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 64654
• Molecular Weight (g/mol): 25.5
• Name: Mouse FGF-23
• Quantity: 2 x 500 μg
• Source: E. coli
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/μg
• Gene Alias: ADHR; FGF; Fgf23; FGF-23; FGFN; Fibroblast growth factor; Fibroblast growth factor 23; Fibroblast growth factor 23 C-terminal peptide; Fibroblast growth factor 23 N-terminal peptide; HPDR2; HYPF; Phosphatonin; PHPTC; tumor-derived hypophosphatemia inducing factor; Tumor-derived hypophosphatemia-inducing factor; UNQ3027/PRO9828
• Gene Symbol: FGF23
• Specific Reactivity: Mouse
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: MYPDTSPLLG SNWGSLTHLY TATARTSYHL QIHRDGHVDG TPHQTIYSAL MITSEDAGSV VITGAMTRRF LCMDLHGNIF GSLHFSPENC KFRQWTLENG YDVYLSQKHH YLVSLGRAKR IFQPGTNPPP FSQFLARRNE VPLLHFYTVR PRRHTRSAED PPERDPLNVL KPRPRATPVP VSCSRELPSA EEGGPAASDP LGVLRRGRGD ARGGAGGADR CRPFPRFV
• Form: Lyophilized
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.