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Invitrogen™ Mouse DIABLO Synthetic Peptide

Product Code. 15206329
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Quantity:
50 μg
Unit Size:
50µg
This item is not returnable. View return policy

Product Code. 15206329

Brand: Invitrogen™ PEP0100

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This item is not returnable. View return policy

Description

Synthetic Peptide

Smac Synthetic Peptide, PEP-0100, from Invitrogen.

DIABLO (smac), a mitochondrial protein, activates various forms of apoptosis. This activation may be due to the neutralization of one or more members of the IAP family of apoptosis inhibitory proteins. Smac exits the mitochondria and enter the cytosol during certain apoptosis triggered events. Mitochondrial-mediated apoptosis is important in animal development and tissue homeostasis, with alterations resulting in a range of malignant disorders. Upon apoptotic stimuli, the mitochondrial proteins cytochrome c and Smac/DIABLO are released into the cytosol. The release of these proteins, however, occurs via different mechanisms. Smac/DIABLO has also been found to play a key role in regulating the sensitization of cancer cells to apoptosis (both immune and drug-induced).
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 66593
Species Mouse
Purification Method purified
Accession Number Q9JIQ3
Common Name Mouse DIABLO
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol Diablo
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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