Invitrogen™ Mouse CD155 (PVR) His-tag Fc Chimera Recombinant Protein

Product Code. 17174283

Brand: Invitrogen™ A42623

Description

Recombinant Protein

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• For Use With (Application): ELISA, Functional Assay, Immunohistochemistry, Western Blot
• Formulation: PBS with 0.01% Tween 80, 5% mannitol, 5% trehalose and no preservative; pH 7.4
• Gene ID (Entrez): 52118
• Molecular Weight (g/mol): 63 kDa
• Name: Mouse CD155 (PVR) His-tag Fc Chimera
• Quantity: 50 μg
• Source: HEK293 cells
• Regulatory Status: RUO
• Endotoxin Concentration: <1.0 EU/ μg
• Gene Alias: 3830421F03Rik; AI325026; AI987993; CD112; CD155; D7Ertd458e; FLJ25946; herpes virus entry mediator B; Herpesvirus entry mediator B; hveB; HVED; mE4; mHveB; Mph; murine herpes virus entry protein B; murine herpesvirus entry protein B; NECL5; necl-5; Nectin cell adhesion molecule 2; Nectin2; Nectin-2; nectin-like 5; nectin-like protein 5; Poliovirus receptor; poliovirus receptor homolog; poliovirus receptor-related 2; poliovirus receptor-related protein 2; poliovirus sensitivity; PVR; Pvrl2; PVS; sCD112; soluble CD112; Taa1; TAGE4; tumor-associated antigen 1; tumor-associated glycoprotein pE4
• Common Name: CD155
• Gene Symbol: PVR
• Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized mouse DNAM1 (at 2 μg/mL (100 μL/well) can bind mouse CD155 with a linear range of 6.4-160 ng/mL)
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: Fc-tag, His-tag
• Sequence: Mouse CD155, amino acids Met1-Arg345 (Accession # NP_081790.1) with a C-terminal His-tagged human IgG1 Fc-tag
• Content And Storage: -20°Cor to +80°C if preferred
• Expression System: HEK293 cells
• Form: Lyophilized
• Purity or Quality Grade: >90% by SDS-PAGE