WNT1, Mouse, Clone: 10C8, Abnova™

Mouse monoclonal antibody raised against recombinant WNT1.

Brand:  Abnova MAB10372.100uL

Product Code. 16000156

Description

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq

Specifications

• Antigen: WNT1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Gene: WNT1
• Gene Symbols: WNT1
• Immunogen: Recombinant protein corresponding to human WNT1.
• Regulatory Status: RUO
• Gene ID (Entrez): 7471
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
• Clone: 10C8
• Description: Mouse monoclonal antibody raised against recombinant WNT1.
• Formulation: In ascites (0.03% sodium azide)
• Gene Alias: INT1
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Liquid