TP63, Mouse, Clone: 4E5, Abnova™

Mouse monoclonal antibody raised against synthetic peptide of TP63.

Brand:  Abnova MAB10290.100uL

Product Code. 16000076

Description

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq

Specifications

• Antigen: TP63
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.
• Gene: TP63
• Gene Symbols: TP63
• Immunogen: A synthetic peptide corresponding to human TP63.
• Regulatory Status: RUO
• Gene ID (Entrez): 8626
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry, Western Blot
• Clone: 4E5
• Description: Mouse monoclonal antibody raised against synthetic peptide of TP63.
• Formulation: In ascites (0.03% sodium azide)
• Gene Alias: AIS/B(p51A)/B(p51B)/EEC3/KET/LMS/NBP/OFC8/RHS/SHFM4/TP53CP/TP53L/TP73L/p40/p51/p53CP/p63/p73H/p73L
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Monkey, Mouse, Rat
• Form: Liquid