TNNI2, Mouse, Clone: 2F12A11, Abnova™

Mouse monoclonal antibody raised against recombinant TNNI2.

Brand:  Abnova MAB10337.100uL

Product Code. 16050116

Description

This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq

Specifications

• Antigen: TNNI2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Gene: TNNI2
• Gene Symbols: TNNI2
• Immunogen: Recombinant protein corresponding to human TNNI2.
• Regulatory Status: RUO
• Gene ID (Entrez): 7136
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
• Clone: 2F12A11
• Description: Mouse monoclonal antibody raised against recombinant TNNI2.
• Formulation: In ascites (0.03% sodium azide)
• Gene Alias: AMCD2B/DA2B/FSSV
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid