SNCA, Mouse, Clone: 2A7, Abnova™

Mouse monoclonal antibody raised against recombinant SNCA.

Brand:  Abnova MAB5383.100uL

Product Code. 16046816

Description

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq]

Specifications

• Antigen: SNCA
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:10000) Immunofluorescence (1:1000) The optimal working dilution should be determined by the end user.
• Gene: SNCA
• Gene Symbols: SNCA
• Immunogen: Recombinant His fusion protein corresponding to human SNCA.
• Regulatory Status: RUO
• Gene ID (Entrez): 6622
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Clone: 2A7
• Description: Mouse monoclonal antibody raised against recombinant SNCA.
• Formulation: In ascites (5mM sodium azide)
• Gene Alias: MGC110988/NACP/PARK1/PARK4/PD1
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mammalia
• Form: Liquid