PARP1, Mouse, Clone: 7A10, Abnova™

Mouse monoclonal antibody raised against synthetic peptide of PARP1.

Brand:  Abnova MAB10291.100uL

Product Code. 16010076

Description

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq

Specifications

• Antigen: PARP1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Gene: PARP1
• Gene Symbols: PARP1
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human PARP1.
• Regulatory Status: RUO
• Gene ID (Entrez): 142
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 7A10
• Description: Mouse monoclonal antibody raised against synthetic peptide of PARP1.
• Formulation: In ascites (0.03% sodium azide)
• Gene Alias: ADPRT/ADPRT1/PARP/PARP-1/PPOL/pADPRT-1
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid