KLK3 Mouse anti-Human, Monoclonal Antibody, Abnova™

Mouse monoclonal antibody raised against native KLK3.

Brand:  Abnova MAB1403.1mg

Product Code. 16019819

Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq

Specifications

• Antigen: KLK3
• Classification: Monoclonal
• Description: Mouse monoclonal antibody raised against native KLK3.
• Formulation: In 15mM KPO₄ buffer, 0.85% NaCl, pH 7.4 (0.09% sodium azide)
• Gene Alias: APS/KLK2A1/PSA/hK3
• Host Species: Mouse
• Quantity: 1 mg
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific to KLK3. No cross-reactivity with human albumin, AFP, CEA, PAP, CA 125, CA 15-3, or CA 19-9.
• Form: Liquid

• Applications: ELISA
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: KLK3
• Gene Symbols: KLK3
• Immunogen: Native purified human KLK3.
• Regulatory Status: RUO
• Gene ID (Entrez): 354
• Content And Storage: Store at 4°C.
• Isotype: IgG2a