KLK3, Mouse, Clone: 8C10B10, Abnova™

Mouse monoclonal antibody raised against full-length native KLK3.

Brand:  Abnova MAB1590.1mg

Product Code. 16043806

Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq

Specifications

• Antigen: KLK3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: KLK3
• Gene Symbols: KLK3
• Immunogen: Native purified human KLK3.
• Regulatory Status: RUO
• Gene ID (Entrez): 354
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA
• Clone: 8C10B10
• Description: Mouse monoclonal antibody raised against full length native KLK3.
• Formulation: In 15mM potassium phosphate buffer, 0.85% NaCl, pH 7.2 (0.05% sodium azide)
• Gene Alias: APS/KLK2A1/PSA/hK3
• Host Species: Mouse
• Quantity: 1 mg
• Primary or Secondary: Primary
• Test Specificity: This antibody reacts with free PSA and PSA-ACT (PSA-alpha 1-antichymotrypsin) complex. There is no cross reactivity with human kallikrein and ACT.
• Form: Liquid