HSP90AB1, Mouse, Clone: MBH90B, Abnova™

Mouse monoclonal antibody raised against synthetic peptide of HSP90AB1.

Brand:  Abnova MAB6458.100ug

Product Code. 16076966

Description

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM

Sequence: EEVHHGEEEVEC

Specifications

• Antigen: HSP90AB1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Immunocytochemistry (1 ug/mL) Western Blot (1 ug/mL) Immunoprecipitation (1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: HSP90AB1
• Gene Symbols: HSP90AB1
• Immunogen: A synthetic peptide corresponding to amino acids at N-terminus of human HSP90AB1.
• Regulatory Status: RUO
• Gene ID (Entrez): 3326
• Target Species: Bovine, Human, Mouse
• Form: Liquid

• Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
• Clone: MBH90B
• Description: Mouse monoclonal antibody raised against synthetic peptide of HSP90AB1.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene Alias: D6S182/FLJ26984/HSP90-BETA/HSP90B/HSPC2/HSPCB
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes the EEVHHG epitope within the N-terminal part of Hsp90b, an ubiquitously expressed protein with calculated MW of 83.3 KDa, however, migrating as a 90 KDa band under reducing SDS-PAGE conditions.
• Content And Storage: Store at 4°C. Do not freeze.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1