EGFR, Mouse, Clone: M199, Abnova™

Mouse monoclonal antibody raised against synthetic phosphopeptide of EGFR.

Brand:  Abnova MAB1382.100uL

Product Code. 16062356

Description

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq

Specifications

• Antigen: EGFR
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:2000) Immunocytochemistry (1:200) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene: EGFR
• Gene Symbols: EGFR
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1101 of human EGFR.
• Regulatory Status: RUO
• Gene ID (Entrez): 1956
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: M199
• Description: Mouse monoclonal antibody raised against synthetic phosphopeptide of EGFR.
• Formulation: In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide)
• Gene Alias: ERBB/ERBB1/HER1/PIG61/mENA
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This human EGFR sequence has high homology to rat and mouse EGFR, and is not conserved in other ErbB family members.
• Form: Liquid