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CYP2A6, Mouse, Clone: F16 P2 D8, Abnova™

Product Code. 16095326
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200 μg
Unit Size:
200µg
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16095326 200 μg 200µg
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Product Code. 16095326 Supplier Abnova Supplier No. MAB1858.200ug

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Mouse monoclonal antibody raised against synthetic peptide of CYP2A6.

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq

Specifications

Antigen CYP2A6
Applications ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone F16 P2 D8
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against synthetic peptide of CYP2A6.
Dilution Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.08% sodium azide)
Gene CYP2A6
Gene Alias CPA6/CYP2A/CYP2A3/P450C2A/P450PB
Gene Symbols CYP2A6
Host Species Mouse
Immunogen A synthetic peptide corresponding to C-terminus of human CYP2A6.
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1548
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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