CPB2 Mouse anti-Human, Monoclonal Antibody, Abnova™

Mouse monoclonal antibody raised against native CPB2.

Brand:  Abnova MAB0276.100ug

Product Code. 16039815

Description

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq

Specifications

• Antigen: CPB2
• Classification: Monoclonal
• Description: Mouse monoclonal antibody raised against native CPB2.
• Formulation: In PBS (50% glycerol)
• Gene Alias: CPU/PCPB/TAFI
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes human TAFI, activated TAFI. Does not inhibit TAFI activation. It inhibits the activated TAFI.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG3

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: CPB2
• Gene Symbols: CPB2
• Immunogen: Native purified HumanCPB2.
• Regulatory Status: RUO
• Gene ID (Entrez): 1361
• Target Species: Human
• Form: Liquid