CD14, Mouse, Clone: biG 14, Abnova™

Mouse monoclonal antibody raised against CD14.

Brand:  Abnova MAB5655.100ug

Product Code. 16280990

Description

CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq

Specifications

• Antigen: CD14
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (1:5000) The optimal working dilution should be determined by the end user.
• Gene: CD14
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: biG 14 represents an excellent marker for CD14. CD14 has been shown to be involved in the LPS-induced cell activation. This antigen is present as a membrane bound form and as soluble antigen, both involved in cell stimulation by LPS. The plasma protein LBP plays an important role in this LPS-CD14 mediated cell activation. Monocytes and PMN are activated by the LBP-LPS complex via membrane CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for Endotoxin.
• Content And Storage: Store at -20°C. For long term storage store at -80°C. After reconstitution with 100μL deionized water it is recommended to add 0.1% BSA. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG2a

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: biG 14
• Description: Mouse monoclonal antibody raised against CD14.
• Formulation: Lyophilized from PBS
• Gene Symbols: CD14
• Immunogen: Monocytes of different species and immunoaffinity purified soluble human CD14.
• Regulatory Status: RUO
• Gene ID (Entrez): 929
• Target Species: Bovine, Canine, Equine, Guinea Pig, Human, Pig
• Form: Lyophilized