C-peptide Mouse anti-Human, Clone: C-PEP-01, Abnova™

Mouse monoclonal antibody raised against C-peptide.

Brand:  Abnova MAB5025.100ug

Product Code. 16066616

Description

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq]

Specifications

• Antigen: C-peptide
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (25 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: INS
• Gene Symbols: INS
• Immunogen: Human C-peptide conjugated with BSA.
• Regulatory Status: RUO
• Gene ID (Entrez): 3630
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry
• Clone: C-PEP-01
• Description: Mouse monoclonal antibody raised against C-peptide.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene Alias: ILPR/IRDN
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody reacts specifically with C-peptide, a part of the Proinsulin molecule. Proinsulin consists of the three parts: C-peptide and two long strands of amino acids (alpha and beta chains; later become linked together to form the Insulin molecule). No cross-reactivity with Insulin or other peptide hormones or proteins was observed.
• Content And Storage: Store at 4°C. Do not freeze.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1