BLNK, Mouse, Clone: 5G9, Abnova™

Mouse monoclonal antibody raised against partial recombinant BLNK.

Brand:  Abnova MAB10505.100uL

Product Code. 16090276

Description

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: BLNK
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Gene: BLNK
• Gene Symbols: BLNK
• Immunogen: Recombinant protein corresponding to human BLNK.
• Regulatory Status: RUO
• Gene ID (Entrez): 29760
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
• Clone: 5G9
• Description: Mouse monoclonal antibody raised against partial recombinant BLNK.
• Formulation: In ascites (0.03% sodium azide)
• Gene Alias: BASH/BLNK-S/LY57/MGC111051/SLP-65/SLP65
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Liquid