Invitrogen™ Mouse Activin A ELISA Kit

Product Code. 18597864

Brand: Invitrogen™ EM3RBX10

Description

ELISA

Mouse Activin A quantitates mouse Activin A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Activin A.

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.

Specifications

• Accession Number: activin A; activin beta-A chain; EDF; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; FRP; FSH-releasing protein; Inhba; Inhibin beta A chain; inhibin beta A subunit; inhibin beta-A; inhibin beta-subunit; inhibin subunit beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); Inhibin, beta-1; unnamed protein product
• Assay Range: 0.5 to 100 pg/mL
• Assay Sensitivity: 0.5 pg/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 16323
• Gene Symbol: Inhba
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 10 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: Activin A
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins